中国科学院长春应用化学研究所化学生物学实验室
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赵传奇
时间:2022-06-02 点击:
 
赵传奇 研究员

学历:博士研究生

学科:无机化学

电话:0431-85262043

邮箱:zhaocq@ciac.ac.cn

地址:吉林省长春市人民大街5625号



简历介绍

19837月生于吉林辽源。中国科学院长春应用化学研究所研究员,博士生导师。2006年毕业于东北师范大学,获学士学位,2012年毕业于中国科学院长春应用化学研究所,获博士学位,毕业后留所工作。主要从事特殊核酸二级结构功能调控以及基于核酸二级结构的抗肿瘤、抗病毒研究。先后主持国家自然科学基金项目4项(包括优青、面上和青年)、中国科学院项目1项以及吉林省自然科学基金项目1项。研究成果发表在J. Am. Chem. Soc., Angew. Chem. Int. Ed.Nucleic acids research.等期刊,参编学术专著2章。研究成果被30余家国际科技媒体给予报道。担任《Exploration》杂志的青年编委。2015年入选中国科学院青年创新促进会会员,2021年获得国家优秀青年科学基金资助。

代表性成果

代表论文:

1. Chuanqi Zhao#, Geng Qin#, Jingsheng Niu, Zhao Wang, Chunyu Wang, Jinsong Ren and Xiaogang Qu*. Targeting Rna G-Quadruplex in Sars-Cov-2: A Promising Therapeutic Target for Covid-19? Angew. Chem. Int. Ed., 2021, 60, 432-438.

2. Zhao Wang, Jingsheng Niu, Chuanqi Zhao*, Xiaohui Wang*, Jinsong Ren and Xiaogang Qu*. A Bimetallic Metal–Organic Framework Encapsulated with Dnazyme for Intracellular Drug Synthesis and Self-Sufficient Gene Therapy. Angew. Chem. Int. Ed., 2021, 60, 12431.

3. Jingsheng Niu, Liangpeng Wang, Tingting Cui, Zhao Wang, Chuanqi Zhao*, Jinsong Ren and Xiaogang Qu*. Antibody Mimics as Bio-Orthogonal Catalysts for Highly Selective Bacterial Recognition and Antimicrobial Therapy. ACS Nano. 2021 15, 15841-15849.

4. Jingsheng Niu, Chuanqi Zhao*, Chun Liu, Jinsong Ren and Xiaogang Qu*. Bio-Inspired Bimetallic Enzyme Mimics as Bio-Orthogonal Catalysts for Enhanced Bacterial Capture and Inhibition. Chem. Mater. 2021, 33, 8052–8058.

5. Yuhuan Sun, Chuanqi Zhao*, Tingting Cui, Hongshuang Qin, Jingsheng Niu, Jinsong Ren and Xiaogang Qu*. Near-Infrared-Traceable DNA Nano-Hydrolase: Specific Eradication of Telomeric G-Overhang in Vivo. Nucleic acids research. 2020, 48, 9986-9994.

6. Yuhuan Sun, Chuanqi Zhao*, Jingsheng Niu, Jinsong Ren and Xiaogang Qu*. Colorimetric Band-Aids for Point-of-Care Sensing and Treating Bacterial Infection. ACS Central Science, 2020, 6, 207-212..

7. Yuhuan Sun, Hongshuang Qin, Zhengqing Yan, Chuanqi Zhao*, Jinsong Ren and Xiaogang Qu*. Combating Biofilm Associated Infection in Vivo: Integration of Quorum Sensing Inhibition and Photodynamic Treatment Based on Multidrug Delivered Hollow Carbon Nitride Sphere. Adv. Funct. Mater., 2019, 29, 1808222

8. Chuanqi Zhao, Hualong Song, Peter Scott, Andong Zhao, Hisae Tateishi-Karimata, Naoki Sugimoto, Jinsong Ren and Xiaogang Qu*. Mirror-Image Dependence: Targeting Enantiomeric G-Quadruplex DNA Using Triplex Metallohelices. Angew. Chem. Int. Ed., 2018, 57, 15723-15727.

9. Andong Zhao, Suzanne E Howson, Chuanqi Zhao*, Jinsong Ren, Peter Scott, Chunyu Wang, Xiaogang Qu*. Chiral Metallohelices Enantioselectively Target Hybrid Human Telomeric G-Quadruplex DNA. Nucleic acids research, 2017, 45, 5026-5035.

10.Chuanqi Zhao, Li Wu, Jinsong Ren, Yan Xu and Xiaogang Qu*. Targeting Human Telomeric Higher-Order DNA: Dimeric G-Quadruplex Units Serve as Preferred Binding Site. J. Am. Chem. Soc., 2013, 135, 18786-18789.

 
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