任劲松课题组董凯同学文章被 Adv. Mater. 接收,文章发表在Adv. Mater. 2013, 25, 4452–4458上。
A new paradigm for an in vivo 980 nm NIRregulated hydrophobic drug-delivery platform has been demonstrated. The drug-delivery vehicle, hollow CuS nanoparticles, with large specifi c surface volume and numerous mesoporous pores, could effi ciently load hydrophobic drug molecules. Additionally, our studies have shown the feasibility of using this nanocarriers as a NIR-triggered and noninvasive remote controlled hydrophobic drug delivery system with high spatial/temperal resolution. We have demonstrated the synergistic effect on killing cancer cells both, in vitro and in vivo, by integrating photothermal therapy and chemotherapy into one system.