恭喜任劲松课题组林友辉文章被Angew. Chem. Int. Ed.接收,文章发表在Angew. Chem. Int. Ed. 2012, 51, 12579 –12583上。
We have described the first example of a label-free, resettable and colorimetric logic network by exploring the combination of the regenerative capability of CeO2 NPs and enzymatic reactions. The distinctive advantage of our CeO2 NP-based logic system is that the biomolecular events can be transformed into color changes, which can be observed by the naked eye. Importantly, the system makes use of thermal control to reset, avoiding any complicated and time-consuming covalent modification or chemical labeling procedure. Moreover, the complexity of the biocomputing systems can be readily scaled up to generate sophisticated networks of logic circuits and mimic natural biological pathways. Furthermore, this work demonstrates ways by which Boolean logic can process information in the field of intelligent diagnostics. Combined together, we expect that this work can be an important starting point for research on CeO2 NP-based logic systems and will be highly beneficial in future biochemical, process control, nanomechanical, and electronic applications.